Legal Article

Analgesic Poisoning: Causes, Symptoms, and Management

Shivendra Pratap Singh


High Court Lucknow


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Published on: 12 Aug, 2023

Analgesics are medications commonly used to relieve pain. They range from over-the-counter drugs like acetaminophen (Tylenol) and aspirin to prescription medications like opioids. While these drugs are beneficial when used as directed, an overdose can lead to serious health problems or even death. In this blog post, we will delve into the causes, symptoms, and management of analgesic poisoning.

1. Causes of Analgesic Poisoning:

Analgesic poisoning can occur due to:

  • Accidental Overdose: This is common among children who might ingest medications mistaking them for candy or among adults who take more than the recommended dose unintentionally.
  • Intentional Overdose: This can be due to a suicide attempt or substance abuse.
  • Chronic Overuse: Taking large doses over an extended period can lead to accumulation and toxicity, even if each dose is not particularly large.

2. Symptoms of Analgesic Poisoning:

The symptoms vary depending on the specific analgesic involved:

  • Acetaminophen (Paracetamol): Early symptoms include nausea, vomiting, loss of appetite, confusion, and sweating. Late symptoms, occurring a few days after the overdose, can include pain in the upper right part of the stomach, yellowing of the skin/eyes (jaundice), and even liver failure.
  • Aspirin and other Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): Symptoms might include nausea, vomiting, abdominal pain, dizziness, tinnitus (ringing in the ears), and, in severe cases, respiratory alkalosis (a condition where the body has too much base, or alkali, due to increased breathing rate) or metabolic acidosis (where the body produces too much acid or the kidneys don’t remove enough acid).
  • Opioids: Overdose symptoms can include pinpoint pupils, drowsiness, confusion, slowed breathing, and even respiratory failure.

3. Management and Treatment:

If you suspect someone has taken an overdose of an analgesic, seek medical attention immediately.

  • Immediate Action: Call emergency services or poison control. If the person is unconscious, lay them on their side and ensure they are breathing. Do not induce vomiting unless directed by a professional.
  • Hospital Treatment: Depending on the severity and type of analgesic ingested, treatments can include:
    • Activated Charcoal: This binds to the drug and reduces its absorption in the stomach.
    • Stomach Pumping: This might be done to remove the remaining pills.
    • Specific Antidotes: For example, N-acetylcysteine is an antidote for acetaminophen overdose, while naloxone is used for opioid overdoses.
    • Supportive Care: This can involve IV fluids, medications to alleviate symptoms, and possibly life support in severe cases.

4. Prevention:

Prevention is always better than cure. Here are some steps to prevent analgesic poisoning:

  • Safe Storage: Always store medications out of reach of children and in their original containers.
  • Proper Disposal: Get rid of unused or expired medications safely.
  • Educate: Ensure everyone in the household understands the importance of taking medications as directed.
  • Limit Access: If someone is struggling with substance abuse or suicidal thoughts, limit their access to large quantities of medications.


Analgesic poisoning is a severe and potentially fatal condition. Always use pain relievers responsibly and as directed by a healthcare professional. If you suspect an overdose, seek medical attention immediately. Remember, timely intervention can save lives.